EDINBURGH, SCOTLAND - NOVEMBER 25: Sean McMahon of Australia breaks the tackle of John Barclay of Scotland during the International match between Scotland and Australia at Murrayfield Stadium on November 25, 2017 in Edinburgh, Scotland. (Photo by Dan Mullan/Getty Images)

The Wallabies have failed to send veteran Stephen Moore out of the game a winner, slumping to an embarrassing 53-24 loss to Scotland in Edinburgh.

The loss was Australia's worst ever defeat to Scotland and the first time the Wallabies have conceded more than 50 points against a team from the northern hemisphere.

With the Wallabies leading 12-10 in a tight match early, prop Sekope Kepu was sent off, leaving the visitors with 14 men for the remainder of the match and Scotland took full advantage.

But coach Michael Cheika refused to blame the extra man for the side's dismal performance.

“The red card was definitely unfortunate but it happens. I don’t think it was a turning point,” Cheika said.

“I thought we still could have won with 14 to be honest. We came back and started off the second half very well.

“We threw away the ball.

“With less players, if you throw away the ball that is sort of what is going to happen.”

Pressure will continue to grow on Cheika following another disappointing performance.

SCOTLAND 53 (B McGuigan 2, J Barclay, A Price, S McInally, S Maitland, J Gray, H Jones tries; F Russell 5 conv, pen goal) defeated AUSTRALIA 24 (T Kuridrani 2, K Beale, L Timani tries; B Foley 2 conv)